Consider recent evidence for a common neural substrate across most psychiatric disorders and describe how these regions may present new targets for brain stimulation treatment.

Consider the clinical challenges of restoring functioning in depressed patients and implement solutions.

Describe how evidence-based treatments impact on motivation and energy in MDD and appreciate the importance and need to restore functioning in these patients.

Consider the evolution of the diagnosis of bipolar disorder and the conceptual framework for the bipolar spectrum in making an accurate diagnosis of bipolar vs. unipolar depression.

Provide a practical explanation of several mindfulness-based therapeutic practices.